Selected Publications

Complete list of publications can be found on ORCID

p53 Regulates Nuclear Architecture to Reduce Carcinogen Sensitivity and Mutagenic Potential
King DA, McCoy DE, Perdyan A, Mieczkowski J, Douki T, Dionne JA, Herrera RE, Morrison AJ (2024).
bioRvix preprint. LINK HERE

Retinoblastoma protein regulates carcinogen susceptibility at heterochromatic cancer driver loci
Wong KM, King DA, Schwartz EK, Herrera RE, Morrison AJ (2022).
Life Science Alliance 4;5(4):e202101134. LINK HERE

Cancer cell metabolism connects epigenetic modifications to transcriptional regulation
Morrison AJ (2021)
FEBS Journal, May 25:10.1111/febs.16032. LINK HERE

Genome-wide profiles of UV lesion susceptibility, repair, and mutagenic potential in melanoma
Perez BS, Wong KM, Schwartz EK, Herrera RE, King DA, García-Nieto PE, Morrison AJ (2021)
Mutation Research 823:111758. LINK HERE

Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction
Rhee S, Paik DT, Yang JY, Nagelberg D, Williams I, Tian L, Roth R, Chandy M, Ban J, Belbachir N, Kim S, Zhang H, Phansalkar R, Wong KM, King DA, Valdez C, Winn VD, Morrison AJ*, Wu JC*, Red-Horse K* (2021) *co-corresponding authors.
European Heart Journal (ehab298). LINK HERE

Chromatin-remodeling links metabolic signaling to gene expression
Morrison AJ (2020).
Molecular Metabolism 38:100973. LINK HERE

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure
Akdemir KC, Le VT, Kim JM, Killcoyne S, King DA, Lin YP, Tian Y, Inoue A, Amin SB, Robinson FS, Nimmakayalu M, Herrera RE, Lynn EJ, Chan K, Seth S, Klimczak LJ, Gerstung M, Gordenin DA, O'Brien J, Li L, Deribe YL, Verhaak RG, Campbell PJ, Fitzgerald R, Morrison AJ, Dixon JR, Andrew Futreal P (2020).
Nature Genetics 52(11):1178-1188. LINK HERE

Recognition of Histone Crotonylation by Taf14 Links Metabolic State to Gene Expression
Gowans GJ, Bridgers JB, Zhang J, Dronamraju R, Burnetti A, King DA, Thiengmany AV, Shinsky SA, Bhanu NV, Garcia BA, Buchler NE, Strahl BD* and Morrison AJ* (2019). *co-corresponding authors
Molecular Cell 76, 909-21.
PUBLICATION LINK HERE UNC NEWS ARTICLE

The somatic mutation landscape of the human body
García-Nieto PE, Morrison AJ, Fraser HB (2019).
Genome Biology. 2019 20(1):298. LINK HERE

INO80 Chromatin Remodelling Coordinates Metabolic Homeostasis with Cell Division
Gowans GJ, Schep AN, Wong KM, King DA, Greenleaf WJ, and Morrison AJ (2018).
Cell Reports 22, 611-23. LINK HERE

Endothelial Deletion of Ino80 Disrupts Coronary Angiogenesis and Causes Congenital Heart Disease
Rhee S, Chung JI, King DA, Duan A, D’amato G, Chang A, Sharma B, Nagelberg D, Jeong Y, Diehn M, Morrison AJ*, Red-Horse K* (2018). *co-corresponding authors
Nature Communications 9:368
PUBLICATION LINK HERE STANFORD NEWS ARTICLE

The INO80 Chromatin Remodeler Sustains Metabolic Stability by Promoting TOR Signaling and Regulating Histone Acetylation
Beckwith SL, Schwartz EK, García-Nieto PE, King DA, Gowans GJ, Wong KM, Eckley TL,
Paraschuk AP, Peltan EL, Lee LR, Yao W, Morrison AJ (2018).
PLOS Genetics 14 (2). LINK HERE

The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding
Zhou CY, Johnson SL, Lee LJ, Longhurst AD, Beckwith SL, Johnson MJ, Morrison AJ, Narlikar GJ (2018).
Molecular Cell 69(4):677-688. LINK HERE

Carcinogen Susceptibility is Regulated by Genome Architecture and Predicts Cancer Mutagenesis
García-Nieto PE, Schwartz E, King DA, Paulsen J, Collas P, Herrera RE and Morrison AJ (2017).
EMBO Journal 36, 2829-43.
PUBLICATION LINK HERE NEWS AND VIEWS LINK

Genome Maintenance Functions of the INO80 Chromatin Remodeller
Morrison AJ (2017).
Philosophical Transactions of the Royal Society B: Biological Sciences 372. LINK HERE

The Arp5-Ies6 Subcomplex Regulates INO80-Mediated Chromatin-Remodeling and Metabolic Potential
Yao W, King D, Beckwith S, Gowans GJ, Yen K, Zhou C, and Morrison AJ (2016). 
Molecular and Cellular Biology 36, 979-91. LINK HERE

Assembly of the Arp5 Subunit Involved in Distinct INO80 Chromatin-Remodeling Activities
Yao W, Beckwith SL, Zheng T, Young T, Dinh VT, Ranjan A, and Morrison AJ (2015).
Journal of Biological Chemistry 290, 25700-9. LINK HERE

Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response
Shanle EK, Andrews FH, Meriesh H, McDaniel SL, Dronamraju R, DiFiore JV, Jha D, Wozniak GG, Bridgers JB, Kerschner JL, Krajewski K, Martin GM, Morrison AJ, Kutateladze TG, and Strahl BD (2015).
Genes & Development 29, 1795-800. LINK HERE

Transcriptome profiling of Set5 and Set1 methyltransferases: Tools for visualization of gene expression
Martín GM, King DA, Garcia-Nieto PE, and Morrison AJ (2014).
Genomics Data 2, 216-18. LINK HERE

Set5 and Set1 Methyltransferases Cooperate to Maintain Chromosome Stability
Martín GM, King D, Greene E, Garcia P, Collins SR, Alexander R, Krogan N, Gozani OP, and Morrison AJ (2014).
Epigenetics 9, 513-22. LINK HERE